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Of Fish, Fly, Worm and Man. Lessons from Developmental Biology for Human Gene Function and Disease

J Kratzschmar, Christiane Nüsslein-Volhard

With the sequencing of several entire genomes, including that of Caenorhabditis elegans, completed, the stage is set for the next phase of "large-scale" biology, the identification of the functionality of, and the interplay between, all genes and their protein products. The aim of the ESRF Workshop 29 and hence of this book was to review the models, the powerful methodology, and selected achievements of developmental biology, which has in the past two decades not only unveiled basic molecular mechanisms of ontogenesis, but also made important contributions to deciphering signal transduction path-ways with general relevance to adult vertebrate physiology and ultimately to understanding mechanisms of pathogenesis.

Par J Kratzschmar, Christiane Nüsslein-Volhard
Chez Springer Verlag

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Sciences de la terre et de la

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01/01/2000 239 pages 74,09 €
Scannez le code barre 9783540663249
9783540663249
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